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(4aS,6R,8aS)-11-[8-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)octyl]-6-hydroxy-3-methoxy-5,6,9,10-tetrahydro-4aH-[1]benzofuro[3a,3,2-ef][2]benzazepin-11-ium

Development stage
Unknown
Modality
Small Molecules
01

Overview

This compound is a synthetic derivative of galantamine featuring a phthalimide-octyl side chain attached to the benzofurobenzazepine core. Galantamine derivatives are typically designed as acetylcholinesterase inhibitors and may also act on nicotinic acetylcholine receptors. These compounds are primarily investigated for their potential in treating neurodegenerative diseases such as Alzheimer's disease by enhancing cholinergic neurotransmission. The specific pharmacological profile and clinical development status of this particular derivative remain unclear from available sources[1][8].

Other names
GALANTHAMINE DERIVATIVEgalanthamine deriv. 4d(4aS,6R,8aS)-11-(8-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)octyl)-6-hydroxy-3-methoxy–5,6,9,10-tetrahydro–4aH-(1)benzofuro(3a , 3 , 2 - ef)(2)benzazepin–11–ium[ACD/IUPAC Name]Compound 711Compound711Compound-711
02

Targets

Acetylcholinesterase

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